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Overview Of Pregabalin

Pregabalin is an analgesic, anticonvulsant, and anxiolytic amino acid, sold under the brand name Lyrica. Most people buy Pregabalin online to relieve neuropathic pain

This medication is U.S. FDA-approved to treat Epilepsy, Fibromyalgia, opioid withdrawals, restless leg syndrome, generalized anxiety disorder (GAD), and shingles. 

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History 

Pregabalin was initially synthesized in the 1970s and used as an anticonvulsant medication in the 1990s. The U.S. FDA approved it for use in 1993, and it has been available as a generic medication in the United States since 2004

Usage

You must buy Pregabalin online if you are suffering from these health conditions:

Seizures Or Epilepsy 

  • Doctors recommend Pregabalin to treat Epilepsy in adults by stopping recurrent seizure episodes and reducing abnormal excitement in the brain that causes seizures.

Generalized Anxiety Disorder (GAD)

  • You can easily buy Pregabalin online if you have a generalized anxiety disorder (GAD). This medication is approved to treat pain by stopping your brain from releasing chemicals that make you feel anxious. 

Restless Leg Syndrome 

  • It improves your sleep structure and periodic limb movements to relieve restless leg syndrome that disturbs your sleep cycle. 

Opioid Withdrawal 

  • This also helps in reducing opioid cravings and withdrawal symptoms caused by overdose or opioid use disorder. 

Fibromyalgia 

  • Pregabalin is also used to treat Fibromyalgia by treating and managing musculoskeletal pain, fatigue, and other symptoms like sleep disorders and cognitive difficulties. 

Neuropathic pain 

  • Most people buy Pregabalin online because it also works as a nerve pain reliever that helps in treating neuropathic pain by calming the body’s nerves. 

How Does It Work?

Pregabalin inhibits the release of excitatory neurotransmitters and stops your brain from releasing chemicals that make you anxious. It reduces abnormal excitement in the brain that leads to anxiety and seizures. 

To treat neuropathic pain, it blocks nerve pain by affecting the pain messages traveling through brain down to the spine. It also stops the release of chemicals from the brain that make a person feel nervous. 

Some buy Pregabalin online due to its rapid onset of action. However, it may take several weeks to begin working for some people. It lasts 30 – 35 hours, and its ingredients remain in your body longer. 

Pill Identification 

Strengths – 50, 75, 100, 150, 200, 225, and 300mg

Color –  Red and white 

Shape – Capsule/oblong

Imprints – Pfizer PGM 

Dosage And Administration 

For Adults

Diabetic neuropathy pain –

  • The initial dose of the immediate-release tablet is 50mg, administered once a day. Based on efficacy and tolerance, the dose may increase up to 100mg within a week.
  • The dose of the extended-release tablet is 165mg, and it is taken orally once a day. The dose may increase up to 330mg within a week and is administered once a day. 

Postherpetic Neuralgia 

  • The recommended dose of the immediate-release tablet is 150mg- 300mg, taken once a day in divided doses. The dose may increase up to 300mg per day; do not take more than 600 mg per day. 
  • The starting dose of the Extended-release tablet is 165 mg, to be taken once a day. 

Epilepsy 

  • The initial recommended dose is 150mg, taken 2 – 3 times daily. The maximum dose is 600mg

Fibromyalgia 

  • The recommended dose is 150mg, which may increase up to 200mg per day.
  • Maintenance dose – 300 – 450mg, and the maximum dose to be used in a day is 450mg

Neuropathic pain 

  • The starting dose for neuropathic pain is 75mg, which may increase to 150mg, and, if easily tolerated, 300 mg taken two to three times a day. Do not exceed a maximum of 600 mg per day. 

Overdose Symptoms 

If you buy Pregabalin online and take it in higher doses, then it can lead to overdose, causing symptoms like – 

  • Ataxia 
  • Severe drowsiness 
  • Slurred speech 
  • Blurred vision 
  • Uncontrolled jerking 
  • Anxiety 

Who Cannot Take Pregabalin?

Anyone can buy Pregabalin online. However, people with certain health conditions are not recommended to use it. 

  • Allergic to Pregabalin or other medicines 
  • Abused or addicted to any drug 
  • Habitual drinking alcohol 
  • On a controlled sodium diet 
  • Kidneys do not work well
  • Severe breathing problems or 
  • A health problem that affects your breathing

Guidelines For Using Pregabalin 

If you buy Pregabalin online for safe and effective use, read the guidelines carefully to prevent any adverse effects. 

  • Avoid using Pregabalin if you have low blood pressure or hypotension.
  • Do not take any anticonvulsant or antidepressant medication during this treatment. 
  • While continuing any other treatment like narcotics, heart medication, or painkillers, avoid taking Pregabalin. 
  • Abrupt or sudden discontinuation of this medication can cause withdrawal symptoms. You must gradually lower the dose and then stop the treatment. 
  • Do not drink alcohol during this medication, as it can lead to severe withdrawal symptoms, reducing its effectiveness. 

Warnings For Special Considerations

  • This medication is not recommended to be used during pregnancy or breastfeeding. 
  • Older adults above 65 years are more at risk of side effects. 
  • Pregabalin should not be given to children below 18 years of age. 

Active Ingredients 

The active ingredient in pregabalin is Lyrica, an anxiolytic amino acid with analgesic and anticonvulsant properties that help treat various health conditions. 

Side Effects 

Pregabalin can cause common to serious side effects, whether you buy Pregabalin online or from an offline store. 

Common side effects 

Some common and most notable side effects of Pregabalin are – 

  • Dizziness 
  • Dry mouth 
  • Headache 
  • Weight gain 
  • Nausea 
  • Sleepiness
  • Constipation 
  • Memory problems 
  • Lack of coordination 

Adverse Effects 

  • Breathing difficulties – It can cause breathing problems when taken with other medications and central nervous system (CNS) stimulants. 
  • Suicidal thoughts – Pregabalin can worsen anxiety or depression, leading to suicidal thoughts. 
  • Vision problems – They may cause decreased eyesight or vision loss. 
  • Mood changes – A person using this medication may become agitated, restless, or aggressive.
  • Heart rhythm problems – Your heart may beat faster or slower than usual.
  • Allergic reactions – In some rare cases, it can cause allergic reactions, such as swelling on face, lips, tongue, or throat. 

Is Pregabalin Safe For Dogs?

Pregabalin can be safely given to dogs for the treatment of seizure disorder and chronic pain under a veterinary recommendation. The standard pregabalin dose for dogs is 4 mg per kg body weight, administered every 12 hours, two to three times a day. 

The most common side effects in dogs are loss of consciousness and sedation. Do not give this medication to dogs with allergic reactions to other medicines. 

How And Where To Buy Pregabalin Online?

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Drug Formulation

Pregabalin combines active ingredients with excipients to create capsules, tablets, and other dosage forms. Pregabalin capsules are composed of 75- 100 parts of Pregabalin, 100 – 500 parts of substituted hydroxypropyl cellulose, and 50 – 100 parts of Clospovidone

Other Brands 

  • Neugaba
  • Pregalin 
  • Pregalift ER
  • Lyrica CR
  • Pregabel, and others

Pregabalin Manufacturers 

The U.S. manufacturers of Pregabalin are Pfizer, Amneal, Teva Pharmaceuticals, Alkem Laboratories, Invagen, Siegen, Alembic, Rising Pharmaceuticals, and MSN Laboratories. 

Conclusion 

This medication has a higher potential for abuse, misuse, and addiction when used regularly for an extended period. People over 65 should talk to a doctor and take a lower dose as recommended for safe use. 

Avoid sharing this medication with children and others without a doctor’s consultation, if you want to buy Pregabalin online. 

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FAQs

  • Are Pregabalin and Lyrica the same?

Lyrica is a brand name for Pregabalin medication that is used to treat neuropathic pain and control seizures and Epilepsy. 

  • Can Pregabalin cause high blood pressure?

Pregabalin helps reduce blood pressure and heart rate through the Nucleus Tractus solitarii PMC. 

  • How does Pregabalin work in the body?

Pregabalin works by releasing excitatory neurotransmitters and blocks nerve pain by affecting the pain messages traveling through the brain down to the spine to treat anxiety, seizures, and neuropathic pain. 

  • Can Pregabalin make you sleepy?

Due to its anticonvulsant properties, Pregabalin effectively improves sleep quality, causing drowsiness.

  • Why does Pregabalin cause weight gain?

Weight gain during this treatment is associated with dosage and time duration. Taking a higher dosage of Pregabalin for a prolonged time can lead to weight gain.